Coli-Dez

Coli-Dez is a bacteriophage-based disinfectant for disinfection of veterinary surveillance facilities using a biological method and prevention of infectious diseases
General provisions
Biological properties
The order of application
Application evaluation criteria
Documents

General provisions

Coli-Dez is a bacteriophage-based disinfectant that contains as an active ingredient a mixture of sterile cell-free phagolysate filtrates (Escherichia phage BF-1372, BF-1373, BF-1374, BF-1375) - 1%, based on sterile saline solution - 99%. The titer of each bacteriophage is at least 1*1010 BOE/ml (according to Grazia). It is intended for carrying out preventive and forced (current and final) disinfection of veterinary surveillance facilities using a biological method. In appearance, it is a transparent liquid, colorless and odorless, and has a neutral pH. The product mixes well with water in any ratio. Packaged in 100ml. Shelf life is 12 months from the date of release, subject to storage and transportation conditions. The medicinal product must be used within 72 hours after opening the vial.

Biological properties

A bacteriophage-based disinfectant, it has the ability to specifically lyse pathogenic Escherichia coli serotypes. The bacteriophages included in the disinfectant are stable in the external environment and compatible with other chemical disinfectants. The bacteriophages included in the disinfectant are stable in the external environment and compatible with other chemical disinfectants. According to the parameters of toxicity when applied to the skin and when injected into the stomach, according to GOST 12.1.007-76, the product belongs to the 4th class of low-risk substances. The range of resistance of bacteriophages to the pH of the external environment is 3.6-9.6. The resistance of bacteriophages to ambient temperature ranges from -80 to +60 ℃.


The order of application

It is designed to ensure effective disinfection by a biological method using bacteriophages of veterinary surveillance facilities. It can be used by aerosol or spray method, depending on the microbiological status and surface, and other features of the veterinary surveillance facility. It can be used by aerosol or spray method, depending on the microbiological status and surface, and other features of the veterinary surveillance facility. It is applied at least before or after 3-4 hours after the current (final) disinfection, the treatment can be carried out both "dirty" and "clean".

Application evaluation criteria

Evaluation of the effectiveness of the drug according to MP 3.5.1.0101—15.